Abstract #3161

Large Deformation Diffeomorphic Metric Mapping for Unlabeled Curves: Application to Fiber Tract Bundles

Yung-Chin Hsu¹, Wen-Yih Isaac Tseng¹,²

¹Center for Optoelectronic Biomedicine, College of Medicine, National Taiwan University, Taipei, Taiwan; ²Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, Taiwan

A registration method for unlabeled curves under the LDDMM framework is proposed, and this method is applied to register two right cingulum bundles for demonstration. The results show that the proposed method could effectively transform the tract bundles so that the global shapes are matched well. By registering the tract bundles to a common space, this method would be a valuable tool to investigate the brain morphology, which is a hot topic in neuroimaging studies in development, ageing or mental disorders.