Abstract #3164

A Multiple-Fibre Diffusion Phantom for the Validation of HARDI Methods

Ezequiel Farrher¹, Farida Grinberg¹, A. Avdo Celik², Kaveh Vahedipour², Nadim Jon Shah²,³

¹Institute of Neuroscience and Medicine 4 - Medical Imaging Physics, Forschungszentrum Juelich, Jlich, Germany; ²Institute of Neuroscience and Medicine 4 - Medical Imaging Physics, Forschungszentrum Jlich, Jlich, Germany; ³Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, Germany

We present a new multiple-fibre design of an anisotropic fibre phantom for diffusion MRI applications. The valuable feature of the new design relates to the integration of several geometrical configurations and fibre populations in a single device. We have demonstrated the application of the design in the analysis of high angular resolution diffusion imaging (HARDI) data analysis methods. The new phantom is shown to be an excellent tool for the investigation and comparison of several of HARDI methods as well as fibre tractography algorithms.