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Abstract #3193

Performance Evaluation of Various Numerical Algorithms for a Multi-Compartmental IVIM-Model

Burkhard Mdler1, Volker A. Coenen2

1Neurosurgery, University Bonn, Medical Centre, Bonn, Germany; 2Divison Stereotaxy and MR-based OR Techniques, University Bonn - Medical Centre, Bonn, Germany

Diffusion-weighted MRI (DWI) is a non-invasive imaging technique that detects thermally driven, random motion of water molecules in living tissue and is able to characterize its interaction with cell membranes, macromolecules and potential diffusion barriers. Le-Bihan proposed a bi-exponential model to separate intra- and extracellular diffusion from incoherent motion of water molecules within randomly oriented capillaries IVIM.