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Abstract #3226

Structural and Functional Changes of Hippocampus in Long Life Experienced Taxi Driver

Geon-Ho Jahng1, Kyung-Mi Lee2, Myung-Won You2, Eo-Jin Hwang3, Min-Ji Kim3, Hyug-Gi Kim4, Dong-Kyun Lee5, Jong-Min Lee5, Chang-Woo Ryu1, Wook Jin1, Dal-Mo Yang1, Ji Seon Park6

1Radiology, Kyung Hee University Hospital at Gangdong, Kyung Hee University, Seoul, Korea; 2Radiology, Graduate College of of Medicine, Kyung Hee University, Seoul, Korea; 3Radiology, Kyung Hee University Hospital at Gangdong, Seoul, Korea; 4Biomedical Engineering, Graduate College of Electronics and Information, Kyung Hee University, Youngin, Gyeonggi-do, Korea; 5Biomedical Engineering, Hanyang University, Seoul, Korea; 6Radiology, Kyung Hee University Hospital, Kyung Hee University, Seoul, Korea

The objective of this study was to investigate the differences of hippocampal volume and shape as well as the functional change between long life experienced taxi drivers and controls of Korean population. Three-dimensional T1-weighted images and blood oxygen level dependent functional MRI(fMRI) were obtained from 8 subjects, consisting of 4 experienced (20 - 30 years) taxi drivers and 4 age-matched controls. The hippocampal volume and shape were analyzed with three-dimensional T1-weighted images. In addition, neuronal activities of brain were analyzed using a blood oxygen level dependent fMRI between the two groups.