Simon Schwab1, Thomas Koenig1, Andrea Federspiel1, Thomas Dierks1, Kay Jann1
1Dept. of Psychiatric Neurophysiology, University Hospital of Psychiatry / University of Bern, Bern, Switzerland
In the present work, we aimed to define the frequency specific thalamic areas generating distinct synchronized cortical networks, as indexed by EEG scalp fields oscillating with a common phase. Fourteen healthy subjects underwent simultaneous EEG/fMRI. The EEG was subjected to a Topographic Time-Frequency Decomposition that formed 6 classes of transient states of synchronized oscillation which were used to fit the thalamic BOLD response. For each of the EEG scalp fields, subregions corresponding to thalamic nuclei were identified. Therefore, our study provides a novel way to elucidate the systematics of subcortical effects on the formation of large scale cortical networks.