Abstract #3288

Data-Driven Parcellation of Resting State Functional Connectivity Networks of the Frontal Lobe in New World and Old World Primates

Li Min Chen¹, Alex V. Maier², Arabinda Mishra¹, Feng Wang¹, Daniel Colvin¹, Allen T. Newton¹, M. Young², John C. Gore¹, Jeffrey D. Schall²

¹Vanderbilt University Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; ²Department of Psychological Sciences, Vanderbilt University, Nashville, TN, United States

Being off-limits to the invasive anatomical techniques, knowledge of human brain connectivity lags behind nonhuman primate. The proposed study is intended to investigate the homology of the primate frontal lobe using a novel imaging approach that bridges the evolutionary division between new world monkeys (Ceboidea) and old world primates (Cercopithecidae). We implemented an unsupervised self-organization mapping1,2 (SOM) technique to study the functional connectivity network of the frontal eye field (FEF) of macaques and squirrel monkeys. Comparison of these connectivity maps across monkey species is a promising initial step to establish the degree of homology of cortical sub-regions in primates.