Amir Abduljalil1, Chima Oluigbo2, Xiangyu Yang1, Andrew Kalnin3, Michael V. Knopp, Ali Rezai2
1Wright Center of Innovation, The Ohio State University, Columbus, OH, United States; 2Neurosurgery, The Ohio State University, Columbus, OH, United States; 3Radiology, The Ohio State University, Columbus, OH, United States
Spinal cord stimulation is an established treatment option for chronic neuropathic pain. However, the cortical processing of sensory information regarding the perception of pain and the stimulation induced pain relief has not yet been well understood. Resting state fMRI and graph theory methodology can provide an insight to the cortical response. In this study, the functional response to four different settings of the spinal cord stimulation was analyzed and significant correlation to the functional brain network measures has been detected.