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Abstract #3300

Reliability of Detecting Functional Connectivity Changes in Alzheimer's Disease

Guangyu Chen1, Chunming Xie1, Guangyu Chen1, Wenjun Li1, B. Douglas Ward1, Jennifer L. Jones2, Malgorzata Franczak2, Piero G. Antuono2, Shi-Jiang Li1

1Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; 2Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, United States


Understanding the reliability of resting-state functional magnetic resonance imaging is essential to the successful application of the technique. This study will demonstrate the key factors that affect the reliability of detecting functional connectivity changes in studying brain disorders.