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Abstract #3315

Characterization and Mitigation of Signal Leakage in Simultaneous Multi-Slice (SMS) Acquisition

Kawin Setsompop1, 2, Stephen F. Cauley3, Himanshu Bhat4, Jonathan R. Polimeni1, 2, Lawrence L. Wald1, 2

1A.A. Martinos Center for Biomedical Imaging, MGH, Charlestown, MA, United States; 2Harvard Medical School, Boston, MA, United States; 3Massachusetts General Hospital, Charlestown, MA, United States; 4Siemens Medical Solutions, Charlestown, MA, United States

Simultaneous Multi-Slice (SMS) acquisition with blipped-CAIPI scheme has enabled dramatic reduction in imaging time for fMRI and Diffusion imaging. The signal leakage is an important metric that characterizes signal corruption (due to leakage of signal from one slice to another) for such an acquisition. . In this work, we demonstrate a technique that can be used to rapidly compute signal leakage metrics, and demonstrate two techniques to modifying the slice-GRAPPA (SG) reconstruction to significantly reduce leakage artifact without affecting the g-factor penalty.