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Abstract #3341

A Quantitative Framework for Interpreting Relationships Between GABA, BOLD FMRI, and Hemodynamic Reactivity in MRI Voxels

Manus J. Donahue1, Swati Rane1

1Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States

The purpose of this work is to outline a quantitative framework for interpreting the primarily correlative relationships that have very recently been reported between blood oxygenation level-dependent (BOLD) contrast and ongoing inhibitory neuronal activity measured by baseline γ-aminobutyric acid (GABA) concentration.