Abstract #3341

A Quantitative Framework for Interpreting Relationships Between GABA, BOLD FMRI, and Hemodynamic Reactivity in MRI Voxels

Manus J. Donahue¹, Swati Rane¹

¹Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States

The purpose of this work is to outline a quantitative framework for interpreting the primarily correlative relationships that have very recently been reported between blood oxygenation level-dependent (BOLD) contrast and ongoing inhibitory neuronal activity measured by baseline γ-aminobutyric acid (GABA) concentration.