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Abstract #3350

Effects of Rapid Head Motions on Group fMRI Functional Connectivity Evaluated with E-REMCOR

Vadim Zotev1, Han Yuan1, Masaya Misaki1, Raquel Phillips1, Kymberly D. Young1, Jerzy Bodurka1, 2

1Laureate Institute for Brain Research, Tulsa, OK, United States; 2College of Engineering, University of Oklahoma, Tulsa, OK, United States

We have applied EEG-assisted retrospective motion correction (E-REMCOR) to evaluate effects of rapid head movements on fMRI functional connectivity data. Twenty MDD patients underwent a resting EEG-fMRI scan. Functional connectivity patterns for seed ROI in the medial prefrontal cortex obtained with and without E-REMCOR were compared. The comparison shows that rapid head movements increase the apparent connectivity strength with the seed ROI for anterior brain regions and reduce it for posterior regions. Our results confirm that effects of head motions are observed in group-level fMRI analysis. They further suggest that E-REMCOR is an efficient motion correction technique for fMRI.