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Abstract #3375

Impact of TWIST View Sharing on Lesion Enhancement Profile in Dynamic Breast MRI

Yuan Le1, Randall Kroeker2, Christian Geppert3, Brian M. Dale4, Hal D. Kipfer1, Chen Lin1

1Radiology and Imaging Science, Indiana University School of Medicine, Indianapolis, IN, United States; 2Siemens Medical Solutions, Winnipeg, Manitoba, Canada; 3Siemens Medical Systems, New York, NY, United States; 4MR R&D, Siemens Medical Solutions, Morrisville, NC, United States

A simulation study was conducted to investigate the impact of TWIST view sharing on the dynamic breast MRI. A digital phantom was generated with spherical lesions of 3-9 mm diameter which exhibit wash-out type of contrast uptake. View sharing strategy, view order and acquisition parameters were identical to actual TWIST sequence and the typical clinical application. The results suggest that, with the same temporal resolution, backward TWIST view sharing provides the best result in tumor edge profile and dynamic enhancement evaluation.