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Abstract #3422

Early Detection of Response to Radiotherapy in Brain Metastases Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Chen-Hao Wu1, 2, Chuan-Han Chen1, Yi-Ying Wu1, Jyh-Wen Chai, Clayton Chi-Cheng Chen, Chung-Ming Chen2, Wen-Yih Isaac Tseng2, 3

1Department of Radiology, Taichung Veterans General Hospital, Taichung, Taiwan; 2Institute of Biomedical Engineering, National Taiwan University, Taipei, Taiwan; 3Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan

Early assessment of metastatic brain tumor response to radiotherapy is vital for treatment optimization for the individual cancer patient. The purpose of this study was to assess the performance of DCE, a novel MRI protocol for apoptosis, as a tool for the early detection of response of brain metastases to radiation therapy.