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Abstract #3425

Multimodality Imaging Assessments of Response to Metformin Therapy for Breast Cancer in Nude Mice

Yi Mao1, Rui xia1, Lei Wang1, yuqing wang1, Fabao Gao1

1Department of Radiology, West China Hospital, Sichuan University, chengdu, sichuan, China

Metformin: A Therapeutic Opportunity in Breast Cancer? Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug? But there is few creditable studies have assessed the in vivo effects of metformin in cancer. We assessed the usefulness of diffusion-weighted imaging (DWI) and bioluminescence imaging (BLI) in evaluating tumor response to metformin.