Abstract #3450

Early Predictive Power of Magnetic Resonance Imaging Parameters During Neoadjuvant Chemotherapy in Uterine Cervical Cancer

Yuki Himoto¹, Koji Fujimoto¹, Aki Kido², Shigeaki Umeoka², Kayo Kiguchi², Fuki Shitano², Tsukasa Baba³, Ikuo Konishi³, Kaori Togashi²

¹Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto, Japan; ²Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Hospital, Kyoto, Japan; ³Department of Gynecology and Obsterics, Kyoto University Hospital, Kyoto, Japan

To evaluate utility of quantitative measurements in MRI for the early prediction of neoadjuvant chemotherapy (NAC) effectiveness in cervical cancer, 13 patients with stage 1b-2b squamous cell carcinoma were assessed. They were performed NAC and radical hysterectomy. Tumor volume, diffusion, and perfusion parameters were correlated to the eventual tumor volume reduction rate after NAC was completed.