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Abstract #3450

Early Predictive Power of Magnetic Resonance Imaging Parameters During Neoadjuvant Chemotherapy in Uterine Cervical Cancer

Yuki Himoto1, Koji Fujimoto1, Aki Kido2, Shigeaki Umeoka2, Kayo Kiguchi2, Fuki Shitano2, Tsukasa Baba3, Ikuo Konishi3, Kaori Togashi2

1Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University, Kyoto, Japan; 2Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Hospital, Kyoto, Japan; 3Department of Gynecology and Obsterics, Kyoto University Hospital, Kyoto, Japan

To evaluate utility of quantitative measurements in MRI for the early prediction of neoadjuvant chemotherapy (NAC) effectiveness in cervical cancer, 13 patients with stage 1b-2b squamous cell carcinoma were assessed. They were performed NAC and radical hysterectomy. Tumor volume, diffusion, and perfusion parameters were correlated to the eventual tumor volume reduction rate after NAC was completed.