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Abstract #3457

Ultrashort Echo Time (UTE) Bi-Component Analysis of Bound and Free Water in Cortical Bone - A Field Dependence Study

Shihong Li1, 2, Won C. Bae1, Eric Chang1, Sheronda Statum1, Christine Chung1, Graeme M. Bydder3, Jiang Du1

1Radiology, University of California, San Diego, San Diego, CA, United States; 2Huadong Hospital, Fudan University, Shanghai, China; 3Radiology, University of California San Diego, San Diego, CA, United States

The existence of two distinct T2* components in cortical bone has been demonstrated in recent studies, where a bi-component model has proven to be superior to a single-component model in fitting ultrashort echo time (UTE) images of cortical bone with progressively increasing TEs. However, all these studies were performed on a clinical 3T whole body scanner. The field dependence of UTE bi-component analysis of cortical bone has not been studied. In this study we investigated how cortical bone bound and free water T2*s and their relative fractions change at 1.5 T and 3 T.