Abstract #3505

Functional 31P-MR Chemical Shift Imaging in Lower Back Muscles During Isometric Load

Patrick Hiepe¹, Alexander Gussew², Reinhard Rzanny³, Jrgen R. Reichenbach³

¹Medical Physics Group, Institute of Diagnostic and Interventional Radiology I , Jena University Hospital, Jena, Germany; ²Medical Physics Group, Institute of Diagnostic and Interventional Radiology I , Jena University Hospital - Friedrich Schiller University Jena , Jena, Germany; ³Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany

This contribution demonstrates the feasibility of applying ³¹P-MR-CSI in lower back muscles during an isometric load to detect and quantify changes of PCr, Pi and pH. For this purpose 14 healthy volunteers were investigated, which performed a modified Srensen test over a time period of 10 min. Load induced changes of phosphorus metabolites and increased SDs of quantified PCr and Pi intensity were observed. The latter is assumed to reflect inter-individual differences for metabolic changes and, thus, for varying degrees of muscle fatigue.