Abstract #3509

Evaluation of Muscle Blood Flow of the Lower-Leg After Exercise Using 3D-PCASL Volume Data

Shuya Fujihara¹, Tosiaki Miyati², Saori Watanabe²,³, Naoki Ohno², Takashi Hamaguchi², Masako Takanaga², Takayuki Miyazaki⁴

¹Division of Health Sciences, Graduate School of Medical Sciences , Kanazawa University, Kanazawa, Ishikawa, Japan; ²Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan; ³Department of Radiology, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan; ⁴School of Health Sciences, College of Medical Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan

To comprehend the clinical physiology of the skeletal muscle disease, direct assessment of the muscle blood flow is essential. However, muscle blood flow (MBF) is the low baseline flow, and which tends to be maintained even in disease states. Thus MBF measurement should test under stress [1]. The objective of our study is to evaluate how much change in the MBF of each lower-leg muscle at the long axis before and after exercise using three-dimensional (3D) pulsed-continuous arterial spin labeling (pCASL) MRI.3D-pCASL makes it possible to obtain volume blood flow data of the lower-leg muscle and evaluate change in regional blood flow of the lower-leg muscle after exercise.