Abstract #3511

In Vivo Diffusion Tensor Imaging of Human Thigh Muscles at 3.0 Tesla

Ke Li¹,², Richard D. Dortch¹,², Ha-Kyu Jeong¹,², Amanda K.W. Buck¹,², Theodore F. Towse,²³, Bruce M. Damon¹,², Jane H. Park⁴

¹Institute of Imaging Science, Vanderbilt University, Nashville, TN, United States; ²Radiology and Radiological Sciences, Vanderbilt University, Nashville, TN, United States; ³Physical Medicine and Rehabilitation, Vanderbilt University, Nashville, TN, United States; ⁴Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, United States

DT-MRI indices from the normal human thigh muscles have particular significance because of the proximal-to-distal presentation of many neuromuscular disorders, causing the thigh muscles to be an early site of pathology. In this work, DT-MRI has been performed in healthy thigh muscles at 3.0 T in order to investigate the normal values obtained by, and the repeatability of, this technique.