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Abstract #3527

Non-Contrast MRI Perfusion Angiosome in Diabetic Feet

Jie Zheng1, Mary K. Hasting1, David Muccigrosso1, Darrah Snozek1, Zhaoyang Fan2, John Curci1, Michael Mueller1

1Washington University in St. Louis, Saint Louis, MO, United States; 2Cedars-Sinal Medical Center, Los Angelas, CA, United States

A non-contrast MRI perfusion angiosome method was developed to assess skeletal muscle perfusion in feet. The study was performed in healthy volunteers and age-matched patients with diabetes mellitus, at rest and during a foot challenge. Significant attenuations in muscle perfusion reserve were observed in diabetic feet, even without developing foot ulcers.