Hon J. Yu1, Dave Michael Hitt2, Hiroshi Yoshioka3
1Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, Irvine, CA, United States; 2U.S. Clinical Science , Philips Healthcare, Cleveland, OH, United States; 3Radiological Sciences, University of California, Irvine, Orange, CA, United States
T1&[rho] scans with varying TSL were performed for T1&[rho] mapping of wrist cartilage at a 3T clinical scanner. The effect of motion correction prior to the fitting for T1&[rho] mapping was tested off-line via ROI-averaged value from the T1&[rho] maps with and without motion correction and also use of R2 map for overall fitting quality. A measurable deviation in ROI-averaged T1&[rho] value of cartilage (up to 22%) occurred even in presence of small mis-alignments in T1&[rho] series (< 1&[deg]/< 0.5 mm in rotation/translation) due to the thin anatomical nature of cartilage. Overall fitting quality improved with motion correction (R2=0.94-0.96 vs. 0.72-0.80). Mapping-based techniques for cartilage require a motion-correction/realignment for more accurate assessment of cartilage.