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Abstract #3557

The Dynamically Changing Default-Mode Network Functional Connectivity After Concussion in Sports

David C. Zhu1, Randy Pearson1, Jeffrey Monroe1, Sally Nogle1, Scarlett Doyle1, Doozie Russell1, Christine Liszewski1, Albert Aniskiewicz1, Michael Shingles1, Douglas Dietzel1, Michael Andary1, J. Kevin DeMarco1, David Kaufman1

1Michigan State University, East Lansing, MI, United States

Resting-state fMRI (rs-fMRI) was applied to understand the dynamics of functional connectivity of the default-mode network and other networks after concussion. It is still unclear if a dynamic recovery process as shown by rs-fMRI is still occurring even after neuropsychological tests return to normal. However, our pilot data clearly demonstrate that rs-fMRI can potentially serve as an important and sensitive tool to monitor the dynamically changing brain function after sports related concussion, and to further our understanding of brain alteration not revealed by neuropsychological and conventional clinical imaging techniques.