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Abstract #3560

Neural Activation Associated with Inhibition Control in Working Memory Maintenance and Its Correlation with Brain Volume Changes in Generalized Anxiety Disorder

Gwang-Won Kim1, Moo-Suk Lee2, Heoung-Keun Kang3, Tae-Jin Park4, Jong-Chul Yang5, Gyung-Ho Chung6, Gwang-Woo Jeong1, 3

1Research Institute of Medical Imaging, Chonnam National University Medical School, Gwangju, Korea; 2Psychiatry, Chonnam National University Medical School, Gwangju, Korea; 3Radiology, Chonnam National University Medical School, Gwangju, Korea; 4Psychology, Chonnam National University, Gwangju, Korea; 5Psychiatry, Chonbuk National University Medical School, jeonju, Korea; 6Radiology, Chonbuk National University Medical School, jeonju, Korea


Patients with generalized anxiety disorder (GAD) is associated with abnormalities in the processing and regulation of cognition, and neuropsychological impairment as well. Despite recent studies for identifying the neural circuitry contributing to cognitive control, the differential neural mechanisms for a delayed-response working memory (WM) and cognitive inhibition components in GAD patients have not yet been specified.

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