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Abstract #3563

Motor Functional Plasticity in Patients with Brain Tumor: The fMRI Study

Chen Niu1, Pan Lin2, Ming Zhang3, Zhigang Min3, Netra Rana3

1The First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, Shaanxi, China; 2Key Laboratory of Biomedical Information Engineering of Education Ministry, Xi'an Jiaotong Universit, Xi'an, Shaanxi, China; 3The First Affiliated Hospital of Medical College, Xi'an Jiaotong University,, Xi'an, Shaanxi, China

Brain plasticity may take place during oncogenesis,Resting-state functional connectivity MRI (fc-MRI) is an effective method to study impaired brain plasticity. However, tumors in or adjacent to primary motor cortex without motor symptoms may disrupt the functional connectivity of the brain. The reason behind this is still unclear. To observe the changes in motor functional plasticity of patients with brain tumor, we compared the functional connectivity between bilateral primary motor cortex (PMC) and supplementary motor area (SMA) of healthy controls and patients with brain tumor. A significant linear correlation between LPMC-SMA and RPMC-SMA was presented in the normal control group. However, no significant correlation was observed between LPMC-SMA and PRMC-SMA in the patient group.