Abstract #3576

Inhibition Network Differences Between ADHD and Healthy Adults Are Unbiased by Drug Use History

Jerod Rasmussen¹, B.J. Casey², Theodorus GM Van Erp¹, Leanne Tamm³, Jeff Epstein³, Claudia Buss¹, James Bjork⁴, James Swanson⁵, Tim Wigal¹, Steven Potkin¹

¹UC Irvine, Irvine, CA, United States; ²Cornell University, New York, NY, United States; ³Cincinnati Children's Hospital, Cincinnati, OH, United States; ⁴NIH, Rockville, MD, United States; ⁵UC Irvine, Irvine, Ca, United States

Persons diagnosed with ADHD in childhood have a higher likelihood of substance abuse at a later age, adding a comorbid factor to attention network deficits brought on by the diagnosis. This work uses the largest sample to date to show that drug use frequency does not bias behavioral and/or cognitive differences when performing a Go/NoGo task. The sample size and multi-site nature of the study make these results especially generalizable.