Abstract #3584

Brain Volume Variation in Female-To-Male Transsexuals

Tae-Hoon Kim¹, Seok-Kwun Kim², Heoung-Keun Kang³, Gwang-Woo Jeong,¹³

¹Research Institute of Medical Imaging, Chonnam National University Medical School, Gwangju, Korea; ²Plastic and Reconstructive Surgery, Donga-A University School of Medicine, Busan, Korea; ³Radiology, Chonnam National University Medical School, Gwangju, Korea

Since sex differentiation of the brain occurs later in development than sex differentiation of genitals, the morphogenesis of the brain plays a critical role in determining gender identity or transsexualism. A few studies investigated the variation of brain structures of male-to-female (MtF) transsexuals. However, no study on the gray matter (GM)-based volume variation of female-to-male (FtM) transsexuals has not yet been studied. This study used a 3 Tesla MRI to compare the volumes of gray matters between FtM transsexuals and female controls using voxel-based morphometry (VBM) analysis.