Tae-Hoon Kim1, Seok-Kwun Kim2, Heoung-Keun Kang3, Gwang-Woo Jeong, 13
1Research Institute of Medical Imaging, Chonnam National University Medical School, Gwangju, Korea; 2Plastic and Reconstructive Surgery, Donga-A University School of Medicine, Busan, Korea; 3Radiology, Chonnam National University Medical School, Gwangju, Korea
Since sex differentiation of the brain occurs later in development than sex differentiation of genitals, the morphogenesis of the brain plays a critical role in determining gender identity or transsexualism. A few studies investigated the variation of brain structures of male-to-female (MtF) transsexuals. However, no study on the gray matter (GM)-based volume variation of female-to-male (FtM) transsexuals has not yet been studied. This study used a 3 Tesla MRI to compare the volumes of gray matters between FtM transsexuals and female controls using voxel-based morphometry (VBM) analysis.