Abstract #3634

Assessment of Tumor Blood Flow in Skull Base Meningiomas and Schwannomas Using Pulsed-Continuous Arterial Spin Labeling Images and Its Correlation with Histopathologic Features

Tatsuya Yamamoto¹, Hiroaki Takeuchi², Yasuhiro Fujiwara³, Hirohiko Kimura¹

¹Department of Radiology, University of Fukui, Fukui, Japan; ²Department of neurosurgery, University of Fukui, Fukui, Japan; ³Division of Radiography, University of Fukui Hospital, Fukui, Japan

No reports have focused on the evaluation of tumor blood flow (TBF) at the skull base. However, we demonstrated a significant difference in TBF between a skull base meningioma and schwannoma. The significant correlation between %TBF and the tumor vessel luminal area (p < 0.01, r_s = 0.83) suggests that precise evaluation of the tumor perfusion state could be accomplished using pulsed-continuous arterial spin labeling. Thus, differential diagnosis of a skull base tumor may be possible to some extent even without the use of contrast material.