Abstract #3640

Associations of Metabolite Concentration and Water Diffusivity in Normal Appearing Brain Tissue with Glioma Grade

Andrew A. Maudsley¹, Bhaswati Roy², Rakesh K. Gupta², Sulaiman Sheriff¹, Rishi Awasthi², Meng Gu³, Nuzhat Hussain⁴, Sudipta Mohakud², Sanjay Behari², Daniel Spielman³

¹Radiology, University of Miami, Miami, FL, United States; ²Radiodiagnostics, SGPGIMS, Lucknow, Uttar Pradesh, India; ³Radiology, Stanford University, Stanford, CA, United States; ⁴Pathology, Ram Manohar Lohia, Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

This study reports changes of tissue metabolism, determined using 1H 3D MRSI, and ADC in tissue regions that are remote from the lesion and appear normal on conventional MRI for subjects with glioma. The associations of these changes with tumor grade are reported.