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Abstract #3752

Free Breathing Abdominal Imaging Via Self-Navigation and Subvolume Registration

Gregory R. Lee1, 2, Yong Chen3, 4, Nicole Seiberlich, 45, Mark A. Griswold3, 4, Vikas Gulani, 46

1Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States; 2Radiology, University of Cincinnati, Cincinnati, OH, United States; 3Radiology, Case Western Reserve University, Cleveland, OH, United States; 4Radiology, University Hospitals of Cleveland, Cleveland, OH, United States; 5Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; 6Radiology, University Hospitals Case Medical Center, Cleveland, OH, United States

Dynamic contrast enhanced imaging of the abdomen is complicated by respiratory motion and often requires multiple breath-holds to be completed. In this work, the properties of a recently developed multi-echo 3D radial acquisition are leveraged to develop a method of self-navigation and subvolume registration. Self-navigation was performed by reconstructing low resolution images every 0.5 seconds to allow the extraction of a pencil-beam navigator. Nonlinear registration of extended duration images corresponding to each respiratory position was performed. Subsequent combination of undersampled images using the corresponding registration parameters allowed rapid, free breathing dynamic abdominal exams to be performed.