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Abstract #3847

Dynamic Quantitative Susceptibility Mapping for Contrast Agent Concentration

Bo Xu1, Tian Liu2, Pascal Spincemaille2, Nanda Deepa Thimmappa2, Martin R. Prince2, Yi Wang1

1Biomedical Engineering, Cornell University, Ithaca, NY, United States; 2Weill Cornell Medical College, New York, United States

A dynamic quantitative susceptibility imaging method is presented for 3D imaging of Gadolinium concentration at sub-second frame rate. A multi-echo flow compensated spiral gradient echo is used for data acquisition. Temporal resolution acceleration with constrained evolution reconstruction is used to generate high temporal frame rate. A morphology enabled dipole inversion with nonlinear formulation is used to generate quantitative susceptibility mapping from complex frame images.