1Biomedical Engineering, Cornell University, Ithaca, NY, United States; 2Weill Cornell Medical College, New York, United States
A dynamic quantitative susceptibility imaging method is presented for 3D imaging of Gadolinium concentration at sub-second frame rate. A multi-echo flow compensated spiral gradient echo is used for data acquisition. Temporal resolution acceleration with constrained evolution reconstruction is used to generate high temporal frame rate. A morphology enabled dipole inversion with nonlinear formulation is used to generate quantitative susceptibility mapping from complex frame images.