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Abstract #3944

Spectrally Interleaved Multi-Echo Sequence for Measurement of Hyperpolarized [1-13C]pyruvate Metabolism

Jae Mo Park1, 2, Yi-Fen Yen1, Priti Balchandani1, 3, Sonal Josan, 14, Ralph Hurd5, Dirk Mayer1, 4, Daniel Spielman1, 2

1Radiology, Stanford University, Stanford, CA, United States; 2Electrical Engineering, Stanford University, Stanford, CA, United States; 3Radiology, Mount Sinai School of Medicine, New York, United States; 4Neuroscience Program, SRI International, Menlo Park, CA, United States; 5Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States

We exploit the long T2 of [1-13C]-labeled pyruvate and metabolic products by developing a spectrally interleaved multi-echo sequence using spectral-spatial RF pulses to increase SNR of the labeled metabolites.