Ivica Just Kukurov1, 2, Ladislav Valkovic1, 3, Martin Gajdosik1, Martin Krssk4, Stephan Gruber1, Tibor Liptaj2, Siegfried Trattnig1, Marek Chmelk1
1MR Centre of Excellence, Department of Radiology, Medical University of Vienna, Vienna, Austria; 2Department of NMR and MS, Faculty of Chemical and Food Technology, Slovak University of Technology, Bratislava, Slovakia; 3Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia; 4Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria
The study aim was to simultaneously assess the composition of fatty acids from the extramyocellular lipids, bone marrow and subcutaneous adipose tissue in the calf at 7T and analyze their saturation profiles. Right calf of four volunteers was scanned using a 2D-CSI sequence with FID and long echo-time acquisition. Ratios of unsaturated fatty-acids (UFA) to CH3 group, polyunsaturated fatty-acids (PUFA) to CH3 group, and PUFA to UFA+PUFA were calculated in: subcutaneous fat, bone marrow and calf muscles. The new 2D-CSI sequence was found suitable for detecting lipids in various tissues for their composition analysis with no extra time needed.