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Abstract #3974

7T Spectroscopic Imaging of the Human Amygdala and Midbrain

Jullie W. Pan1, Hoby P. Hetherington2

1Neurosurgery, Yale University School of Medicine, New Haven, CT, United States; 2Yale University, New Haven, CT, United States

In the brain, the amygdala is believed to function in the processing of emotion and memory, and has been shown to be dysfunctional in many psychological and psychiatric disorders such as post-traumatic stress and bipolar disorders. The MR evaluation of the amygdala can be challenging however, because of its inferior temporal-frontal location lateral to the cavernous sinus, and is particularly problematic for ultra-high field studies. In this study we describe implementation of high degree shimming to perform J-refocused spectroscopic imaging using in the region of the midbrain and amygdala at 7T.