Meeting Banner
Abstract #4075

Separate Assessment of Fibrosis, Steatosis and Inflammation: Multi-Parametric Imaging of Chronic Liver Diseases

Sabrina Doblas1, Helena S. Leitao1, 2, Philippe Garteiser1, Gaspard d'Assignies1, 3, Feryel Mouri4, Valrie Vilgrain1, 3, Ralph Sinkus1, Carlos F.G.C. Geraldes2, Bernard E. Van Beers1, 3

1U773-CRB3, INSERM, Paris, France; 2Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal; 3Radiology Department, Beaujon University Hospital, Clichy, France; 4Hepatology Department, Beaujon University Hospital, Clichy, France

Confounding factors such as steatosis and inflammation can bias the evaluation of hepatic fibrosis by MR elastography or DWI, 2 techniques proposed as non-invasive approaches to the evaluation of chronic liver diseases. Multivariate analysis of MR elastography and DWI data obtained from a cohort of 58 hepatitis patients showed that viscoelastic parameters preferentially responded to fibrosis, whereas the diffusion coefficient was mostly affected by steatosis.