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Abstract #4077

Measurement of Liver and Splenic Stiffness with MR Elastography Using Single or Double Acoustic Excitation.

Hadrien A. Dyvorne1, Guido H. Jajamovich1, Richard L. Ehman2, Ersin Bayram3, Bachir Taouli1, Richard L. Ehman2

1Mount Sinai School of Medicine, New York, NY, United States; 2Department of Radiology, Mayo Clinic, Rochester, MN, United States; 3GE Healthcare, Waukesha, WI, United States

Two techniques for measuring liver and splenic stiffness using MR elastography were compared. The first uses a single acoustic driver located on the organ of interest, and performs two different acquisitions (one for each organ). The second technique aims to calculate both liver and splenic stiffness from a single acquisition, by using two drivers exciting both organs in parallel. Liver and splenic stiffness values were compared in 29 subjects and were found to be in good agreement between the two techniques. A comparison between cirrhotic and non cirrhotic populations revealed significantly higher stiffness values in liver and spleen in cirrhotic subjects.