Hemodynamic Changes in Healthy and Cirrhotic Liver Measured Using a Breath-Hold High Resolution, Highly Accelerated K-T SPARSE-SENSE Phase Contrast Sequence.

Hadrien A. Dyvorne¹, Ashley Knight-Greenfield¹, Nancy Cooper¹, Cecilia Besa¹, Ricardo Otazo², Daniel K. Sodickson², Bachir Taouli¹

A high resolution, highly accelerated phase contrast (PC) sequence using a joint compressed sensing and parallel imaging approach (k-t SPARSE-SENSE) was used for the detection of hemodynamic changes in non cirrhotic and cirrhotic liver within a single breath-hold. The high spatial resolution provided by the technique allowed for better depiction of the hepatic artery as compared to a conventional parallel imaging PC. When comparing flow parameters of non cirrhotic and cirrhotic subjects, we observed significantly decreased portal vein velocity and increased arterial fraction in cirrhotic subjects.