Abstract #4093

Adiabatic Spin Locking T1rho Imaging for Estimation of Liver Function

Tomoyuki Okuaki¹, Yukihisa Takayama², Akihiko Nishie³, Makoto Obara⁴, Tetsuo Ogino⁴, Hiroshi Honda³, Marc Van Cauteren¹

¹Philips Healthcare Asia Pacific, Minato-ku, Tokyo, Japan; ²Department of Molecular Imaging and Diagnosis, Kyushu University, Graduate School of Medical Science, Fukuoka, Japan; ³Department of clinical Radiology, Kyushu University, Graduate School of Medical Sciences, Fukuoka, Japan; ⁴Philips Electronics Japan, Minato-ku, Tokyo, Japan

An adiabatic locking pulse is applied to obtain homogeneous spin locking and compared with block pulse locking. Visual evaluation was done to assess the homogeneous of the T1rho maps and T1rho values obtained by both methods were measured. The visual evaluation of T1rho maps obtained by adiabatic locking was scored higher (p value<0.05) and T1rho values obtained by adiabatic were significantly different between normal and Child-Pugh BorC(Kruskal-Wallis method, p value<0.05). Adiabatic spin locking method provided homogeneous and artifact free liver T1rho maps at 3T. This is expected to be useful for robust evaluation of liver function using T1rho.