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Abstract #4110

Respiratory 3D Cine MRI of Upper Airway Dynamics in Obstructive Sleep Apnea

Mark E. Wagshul1, Sanghun Sin2, David M. Wootton3, Michael L. Lipton1, 4, Keivan Shifteh4, Raanan Arens2

1Radiology, Gruss MRRC, Albert Einstein College of Medicine, Bronx, NY, United States; 2Pediatrics, Montefiore Medical Center, Bronx, NY, United States; 3Mechnical Engineering, The Cooper Union for the Advancement of Science and Art, New York, NY, United States; 4Radiology, Montefiore Medical Center, Bronx, NY, United States

Retrospective, 3D cine imaging using respiratory gating has the ability to demonstrate high resolution, dynamic imaging of the upper airway. This is an important technique for studying airway motion in obstructive sleep apnea syndrome (OSAS), and will ultimately allow accurate modeling of upper airway motion for designing optimal treatments. Cine imaging was used in 24 adolescents being evaluated for polycystic ovary syndrome, a condition with high OSAS prevalence. In two OSA patients with severe obstruction of the upper airway, the technique allowed visualization of asynchronous airway motion, compared to mostly synchronous airway motion in non-OSAS patients.