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Abstract #4199

Enhanced Contrast of Superparamagnetic Iron Oxide Contrast Agents by Spin-Lock MR

Rik P.M. Moonen1, Pieternel van der Tol1, Stefanie J.C.G. Hectors1, Klaas Nicolay1, Gustav J. Strijkers1

1Biomedical Engineering/ Biomedical NMR, Eindhoven University of Technology, Eindhoven, Netherlands

In this in vitro study we show that T1ρ provides enhanced sensitivity for the detection of SPIO and USPIO contrast agents in comparison to T2. ΔR1ρ values at 1.41 T of agar gels containing different concentrations of Sinerem and Resovist were respectively up to 4.8-fold and 6.6-fold higher as compared to ΔR2.