Abstract #4199

Enhanced Contrast of Superparamagnetic Iron Oxide Contrast Agents by Spin-Lock MR

Rik P.M. Moonen¹, Pieternel van der Tol¹, Stefanie J.C.G. Hectors¹, Klaas Nicolay¹, Gustav J. Strijkers¹

¹Biomedical Engineering/ Biomedical NMR, Eindhoven University of Technology, Eindhoven, Netherlands

In this in vitro study we show that T_1ρ provides enhanced sensitivity for the detection of SPIO and USPIO contrast agents in comparison to T₂. ΔR_1ρ values at 1.41 T of agar gels containing different concentrations of Sinerem and Resovist were respectively up to 4.8-fold and 6.6-fold higher as compared to ΔR₂.