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Abstract #4205

Iron and Myelin Induced Contrast Variations in the Corpus Callosum

Christian Langkammer1, Nikolaus Krebs2, Walter Goessler3, Eva Scheurer2, Franz Fazekas1, Stefan Ropele1

1Department of Neurology, Medical University of Graz, Graz, Austria; 2Ludwig Boltzmann Institute for Clinical-Forensic Imaging, Graz, Austria; 3Institute of Analytical Chemistry, University of Graz, Graz, Austria

This study provides regional reference values for iron concentrations in the corpus callosum and demonstrates a heterogeneous distribution along the corpus callosum. These variations substantially impact R2* and, thus, will consequently impact also phase and bulk susceptibility.