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Abstract #4222

Intervertebral Disc CEST Imaging with Improved Reliability Using Reduced-FOV TSE

Qi Liu1, 2, Ning Jin3, Zhaoyang Fan1, Yutaka Natsuaki4, Wafa Tawackoli1, Dan Gazit1, Gadi Pelled1, Debiao Li1, 5

1Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States; 2Biomedical Engineering, Northwestern University, Chicago, IL, United States; 3Siemens Medical Solutions, Columbus, OH, United States; 4Siemens Healthcare, Los Angeles, CA, United States; 5University of California, Los Angeles, los angeles, CA, United States

A reduced-field-of-view (rFOV) TSE method is used to reliably measure IVD gagCEST signal in vivo by reducing bowel movement artifacts on a 3.0T clinical scanner. The proposed method is verified by a phantom study, and is compared with the conventional full-FOV CEST technique on nine volunteers.