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Abstract #4283

Application of a Non-CPMG Single-Shot Turbo Spin Echo Sequence to Multi-Contrast Imaging of the Human Lung at 1.5T

Flavio Carinci1, 2, Morwan Choli, 23, Felix A. Breuer3, Peter M. Jakob, 23

1MRB Research Center, Wuerzburg, Germany; 2Department of Experimental Physics 5, University of Wuerzburg, Wuerzburg, Germany; 3Research Center Magnetic Resonance Bavaria e. V. (MRB), Wuerzburg, Germany

Magnetic resonance imaging of the lung is challenging due to low proton density, short T2*, respiratory and cardiac motion. Single-shot turbo spin-echo (ssTSE) sequences can be used to obtain good signal-to-noise ratio in the lungs and to suppress motion artifacts. However preparation schemes such as diffusion and T2* preparation can result in the violation of the CPMG conditions and generate severe artifacts. In this work we present the application of a non-CPMG ssTSE sequence to diffusion-weighted and T2*-weighted imaging of the human lung. We show that this approach allows for apparent diffusion coefficient (ADC) and T2* mapping of the human lung in a single 10s breath-hold.