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Abstract #4296

Assessment of Temperature Induced Changes of T1 and T2 Relaxation Times in the Human Brain

Christoph Birkl1, Christian Langkammer1, Johannes Haybaeck2, Christina Ernst2, Rudolf Stollberger3, Franz Fazekas1, Stefan Ropele1

1Department of Neurology, Medical University of Graz, Graz, Austria; 2Department of Neuropathology, Institute of Pathology, Medical University of Graz, Graz, Austria; 3Institute of Medical Engineering, Graz University of Technology, Graz, Austria

In this work we investigated the temperature dependency of T1 and T2 relaxation times in the human brain. Our results confirmed the predicted temperature dependency of T1 but showed a strong difference between the brain structures. The temperature dependency of T2 is to small to measure because it is masked out by different effects. This work provides for the first time detailed temperature dependency values of the human brain and can be used to improve MR thermometry or to translate findings from postmortem MR to in-vivo data.