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Abstract #4450

Vessel Segmentation with 4D Flow MRI for the Characterization of Blood Mixing in Single Ventricle Patients After the Fontan Procedure

Kelly Jarvis1, Susanne Schnell1, Ramona Lorenz2, Alejandro Roldn-Alzate3, Kevin M. Johnson3, Maya Gabbour4, Joshua D. Robinson, 45, Cynthia K. Rigsby, 14, Michael Markl1

1Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States; 2Radiology, University Medical Center Freiburg, Freiburg, Germany; 3Radiology and Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI, United States; 4Medical Imaging and Cardiology, Ann & Robert H. Lurie Childrens Hospital of Chicago, Chicago, IL, United States; 5Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States


Single ventricle patients have a complex form of congenital heart disease and undergo multiple surgeries, resulting in the Fontan vasculature geometry. There is growing evidence that underlying hemodynamics in the Fontan circulation may play an important role in patient outcome. The aim of this study was to isolate flow at the Fontan connection by integrating anatomical image segmentation into the 4D flow MR analysis work flow for improved flow visualization and mixing quantification.

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