Abstract #4491

A Qualitative and Quantitative Assessment of Real-Time Cardiac Functional Imaging Using Through-Time Radial GRAPPA

Vidya Nadig¹, Victoria Yeh², Gunhild Erstad Aandal³, Prabhakar Rajiah³, Trevor Jenkins⁴, Abdus Sattar⁵, Mark A. Griswold³,⁶, Vikas Gulani,⁶⁷, Robert Chapman Gilkeson³, Nicole Seiberlich⁶

¹Cardiology, MetroHealth Medical Center at Case Western University, Cleveland, OH, United States; ²Case Western Reserve University School of Medicine, Cleveland, OH, United States; ³Dept. of Radiology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, OH, United States; ⁴Cardiology, University Hospitals of Cleveland, Cleveland, OH, United States; ⁵Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, United States; ⁶Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; ⁷Dept. of Radiology, Case Western Reserve University, Cleveland, OH, United States

Temporal resolutions <50 ms can be achieved using through-time radial GRAPPA for CMR, obviating need for gating or breathholding. In this study, 41 subjects underwent functional cardiac imaging using standard breathhold cine and real-time imaging (with through-time radial GRAPPA). Bland-Altman analysis of LVEF from the two methods showed 39/40 of measurements within 95% limits of agreement, and the mean difference was -1.9%. Radiologists rating showed >90% of qualitative parameters for both methods were in the excellent or good visibility range. This indicates that real-time imaging could replace breathhold cine, and be used for patients with arrhythmia or difficulty breathholding.