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Abstract #4522

Assessment of Non-Linearities in Cardiac Perfusion Measurements Using Low-TI AIF Images

Felix Schwab1, Lena Vomacka1, Daniel Theisen1, Maximilian F. Reiser1, Olaf Dietrich1

1Institute for Clinical Radiology, Ludwig-Maximilian-University Hospital Munich, Munich, Bavaria, Germany

This abstract investigates the potential of Low TI saturation recovery sequences to assess non-linearities in cardiac perfusion analyses. The corresponding sequences appear to be well described by a linear approximation and demonstrate that standard clinical protocols are afflicted with significant non-linearities and thus overestimate perfusion parameters. Arterial input functions calculated from the low TI protocols can circumvent this problem.