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Abstract #4541

Fast Relaxation Time Mapping in Human Carotid Artery Wall Using Black Blood DANTE 2D Turbo Spin Echo

Linqing Li1, Luca Biasiolli2, Matthew D. Robson2, Karla L. Miller1, Peter Jezzard1

1FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom; 2Department of Cardiovascular Medicine, University of Oxford, Oxford, United Kingdom

DANTE prepared 2D-TSE has previously been demonstrated effective application of fast BB imaging. In this work, we first derived a highly simplified linear equation M=M0[1-1/2(T1/T2)1/2] from the longitudinal Bloch equation at steady state of DANTE pulses. Equation was then verified to be applicable when DANTE pulse train is interspersed with readout modules. Finally, in-vivo BB experiments for T1 and T2 mapping demonstrate that DANTE-TSE has potential to be applied as fast (3measurements in 10minutes with 39slices), high resolution (0.60.62mm) and robust (insensitive to susceptibility in both preparation and readout module) imaging tool for relaxation time mapping carotid artery walls.