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Abstract #0035

in vivo Ultrafast Diffusion Imaging of Stroke at 21.1 T by Spatiotemporal Encoding

Jens T Rosenberg 1,2 , Avigdor Leftin 3 , Eddy Solomon 3 , Fabian Calixto Bejarano 1 , Lucio Frydman 1,3 , and Samuel Colles Grant 1,2

1 National High Magnetic Field Laboratory, The Florida State University, Tallahassee, FL, United States, 2 Chemical & Biomedical Engineering, The Florida State University, Tallahassee, FL, United States, 3 Chemical Physics, Weizmann Institute of Science, Rehovot, Israel

Fast imaging techniques such as echo planar imaging (EPI) are popular techniques for imaging of neuronal injuries. However, there is an inherent problem with these techniques with respect to susceptibility and geometric artifacts that distort not only anatomical information but also the quantification of relevant quantities, such as water diffusion. To provide robust and fast acquisitions at high field, this study utilizes an ultrafast single-shot spatiotemporally encoded (SPEN) imaging sequence with diffusion encoding to measure apparent diffusion coefficient (ADC) in stroke. Results show that SPEN images provide a more accurate way of measuring ADC at high field compared to EPI.

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