Abstract #0103
Resolving Myelin and Axonal Properties within the Same Voxel in Presence of Crossing Fibers by Combining Inversion Recovery and Diffusion Acquisitions
Silvia De Santis 1,2 , Daniel Barazany 1,2 , Derek K Jones 1 , and Yaniv Assaf 2
1
School of Psychology, CUBRIC, Cardiff, UK,
United Kingdom,
2
Department
of Neurobiology, Tel Aviv University, Tel Aviv, Israel,
Israel
The purpose of this work is to develop a new
acquisition&analysis strategy, by combining inversion
recovery with conventional diffusion tensor imaging, and
by acquiring CHARMED protocol to calculate fiber
orientations and volume fractions. For each fiber
population present within a voxel, we extract a specific
longitudinal relaxation time T1 by exploiting the
orientational dependence of the diffusion-weighted
signal that has been previously inversion-prepared. As
the relaxation time T1 has been established as a solid
proxy for myelination, this method effectively succeeds,
for the first time, to resolve both axonal and myelin
properties in presence of crossing fibers.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
