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Abstract #0113

Carotid Multicontrast Atherosclerosis Characterization (MATCH) in a Single Scan: Technical Development and Preliminary Validation

Zhaoyang Fan 1 , Yibin Xie 1,2 , Wei Yu 3 , Antonio H. Conte 1 , Xiaoming Bi 4 , Yutaka Natsuaki 4 , Gerhard Laub 4 , Jing An 5 , Prediman K. Shah 1 , and Debiao Li 1

1 Cedars-Sinai Medical Center, Los Angeles, CA, United States, 2 University of California, Los Angeles, CA, United States, 3 Anzhen Hospital, Beijing, China, 4 MR R&D Siemens Healthcare, Los Angeles, CA, United States, 5 MR Collaborations NE Asia, Siemens Healthcare, Beijing, China

The conventional MRI protocol for the characterization of atherosclerotic plaques involves a series of scans that provide multiple contrast weightings. Despite the success in previous investigations, it has some major limitations such as limited slice resolution, substantially long examination time, image registration needed due to interscan motion. This work developed a 3D MRI technique that acquires multiple image sets in a single 5-minute scan with distinct contrast weightings that help simplify compositional analysis in carotid plaques. Preliminary healthy volunteer and patient studies were performed to demonstrate the promise of this technique in a clinical setting.

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